Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95398 | 0.89 | HSD17B10 (0.39) | HSD17B10ALOX15ALOX12AKR1B1TDP1 | |
| SCHEMBL4315763 | 0.80 | HSP90AA1 (0.38) | HSD17B10ALOX15ALOX12AKR1B1TDP1 | |
| SCHEMBL13865241 | 0.80 | HSD17B10 (0.38) | HSD17B10ALOX15ALOX12AKR1B1TDP1 | |
| SCHEMBL13865237 | 0.76 | HSD17B10 (0.38) | HSD17B10ALOX15ALOX12AKR1B1TDP1 | |
| SCHEMBL6822649 | 0.76 | ALOX15 (0.42) | HSD17B10ALOX15ALOX12TDP1ALDH1A1 | |
| SCHEMBL3803700 | 0.72 | TDP1 (0.45) | HSD17B10ALOX15ALOX12AKR1B1TDP1 | |
| SCHEMBL2123860 | 0.69 | ALOX15 (0.34) | HSD17B10ALOX15ALOX12AKR1B1TDP1 | |
| SCHEMBL6060636 | 0.67 | HSP90AA1 (0.35) | ALDH1A1 | |
| SCHEMBL13868098 | 0.64 | RAB9A (0.31) | — | |
| SCHEMBL13369758 | 0.61 | CA2 (0.42) | HSD17B10ALOX15ALOX12TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088080-A1 | ANTIMONY TRIOXIDE FREE FLAME RETARDANT THERMOPLASTIC COMPOSITION | ICL-IP AMERICA INC. (US) | 2012-06-28 | — | — | WO | disclosed |