Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434512 | 0.85 | HSP90AA1 (0.49) | HSP90AA1ALDH1A1KMT2A | |
| SCHEMBL1834886 | 0.81 | ALDH1A1 (0.36) | ALDH1A1BACE1NOS1NQO2AXL | |
| SCHEMBL95398 | 0.75 | HSD17B10 (0.39) | MEN1ALDH1A1KMT2ANQO2LMNA | |
| SCHEMBL6266803 | 0.75 | KMT2A (0.37) | MEN1ALDH1A1KMT2ABACE1NOS1 | |
| SCHEMBL5968103 | 0.73 | LMNA (0.44) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8864422 | 0.70 | ACHE (0.41) | HSP90AA1MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL5424007 | 0.69 | POLB (0.33) | KMT2ANQO2LMNASMN1; SMN2NPC1 | |
| SCHEMBL5428096 | 0.69 | POLB (0.33) | KMT2ANQO2LMNASMN1; SMN2NPC1 | |
| SCHEMBL6060985 | 0.69 | — | — | |
| SCHEMBL4315763 | 0.67 | HSP90AA1 (0.38) | HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1273621-B1 | FLAME-RETARDANT POLYOLEFIN RESIN COMPOSITION | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-6924331-B2 | Flame-retardant polyolefin resin composition | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| US-20030139507-A1 | Flame-retardant polyolefin resin composition | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1273621-A1 | FLAME-RETARDANT POLYOLEFIN RESIN COMPOSITION | Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) | 2003-01-08 | — | — | EP | disclosed |