Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132535 | 0.80 | HCAR2 (0.52) | HCAR2 | |
| SCHEMBL938157 | 0.80 | HCAR2 (0.52) | HCAR2 | |
| Hydrochloric Acid SCHEMBL2134245 | 0.78 | HCAR2 (0.50) | HCAR2 | |
| Hydrochloric Acid SCHEMBL2134248 | 0.78 | HCAR2 (0.50) | HCAR2 | |
| SCHEMBL663907 | 0.77 | HCAR2 (0.52) | HCAR2 | |
| SCHEMBL663908 | 0.77 | HCAR2 (0.52) | HCAR2 | |
| SCHEMBL255887 | 0.77 | — | — | |
| SCHEMBL692137 | 0.77 | — | — | |
| SCHEMBL3706927 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28375076 | 0.76 | HCAR2 (0.31) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180177767-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. (US) | 2018-06-28 | — | — | US | disclosed |
| US-20120046494-A1 | METHOD OF PREPARING AN ALKYLAMINE DERIVATIVE | KOLON LIFE SCIENCE, INC. (KR) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046494-A1 | METHOD OF PREPARING AN ALKYLAMINE DERIVATIVE | INMT, PNMT, ALKBH2 | HCAR2 3189/4885 |
| US-20180177767-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | KRAS, NRAS, HRAS | HCAR2 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.