Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144281 | 0.83 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL28771911 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8541344 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL9787607 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL8824721 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL25779596 | 0.75 | — | — | |
| SCHEMBL8536293 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL4163347 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL2154609 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL22661237 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-8066970-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2011-11-29 | — | — | US | disclosed |
| US-20090053142-A1 | CONTRAST AGENTS | WYNN DUNCAN | 2009-02-26 | — | — | US | disclosed |
| US-20070264201-A1 | Contrast Agents | GE HEALTHCARE LIMITED (NO) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053142-A1 | CONTRAST AGENTS | IPO4, TPO, IPO11 | ALDH1A1 3352/4885 |
| US-20070264201-A1 | Contrast Agents | TPO, IPO4, IPO11 | ALDH1A1 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.