Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997306 | 0.88 | HDAC4 (0.59) | HDAC4ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL30182558 | 0.88 | HDAC4 (0.59) | HDAC4ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL6996658 | 0.87 | ALDH1A1 (0.64) | HDAC4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7826321 | 0.86 | HDAC4 (0.58) | HDAC4ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL39437 | 0.84 | EGFR (0.48) | HDAC4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11983226 | 0.84 | EGFR (0.56) | HDAC4ALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL10044897 | 0.83 | KDM4E (0.51) | HDAC4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15154436 | 0.82 | HDAC4 (0.54) | HDAC4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15164761 | 0.82 | AHR (0.55) | HDAC4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12254514 | 0.82 | HIF1A (0.52) | HDAC4KDM4ETSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277693-A1 | A PHARMACEUTICAL PRODUCT CONTAINING TASQUINIMOD AND A METHOD FOR ASSESSING THE PURITY OF SAID PRODUCT | ACTIVE BIOTECH AB (SE) | 2024-08-22 | — | — | US | disclosed |
| EP-4363404-A1 | A PHARMACEUTICAL PRODUCT CONTAINING TASQUINIMOD AND A METHOD FOR ASSESSING THE PURITY OF SAID PRODUCT | Active Biotech AB (SE) | 2024-05-08 | — | — | EP | disclosed |
| CN-117500790-A | Pharmaceutical product containing taquinimod and method for evaluating purity of said product | 活跃生物技术有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023275248-A1 | A PHARMACEUTICAL PRODUCT CONTAINING TASQUINIMOD AND A METHOD FOR ASSESSING THE PURITY OF SAID PRODUCT | ACTIVE BIOTECH AB (SE) | 2023-01-05 | — | — | WO | disclosed |
| EP-2723340-B1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | ACTIVE BIOTECH AB (SE) | 2017-11-22 | — | — | EP | disclosed |
| US-9216956-B2 | Deuterium-enriched 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide | ACTIVE BIOTECH AB (SE) | 2015-12-22 | — | — | US | disclosed |
| EP-2590949-B1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| EP-2590949-B1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| US-8871936-B2 | Method for manufacturing of quinoline-3-carboxamides | ACTIVE BIOTECH AB (SE) | 2014-10-28 | — | — | US | disclosed |
| US-8871936-B2 | Method for manufacturing of quinoline-3-carboxamides | ACTIVE BIOTECH AB (SE) | 2014-10-28 | — | — | US | disclosed |
| US-8871936-B2 | Method for manufacturing of quinoline-3-carboxamides | ACTIVE BIOTECH AB (SE) | 2014-10-28 | — | — | US | disclosed |
| US-20140112946-A1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | ACTIVE BIOTECH AB (SE) | 2014-04-24 | — | — | US | disclosed |
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2013-05-02 | — | — | US | disclosed |
| EP-2537517-A1 | Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide | Active Biotech AB (SE) | 2012-12-26 | — | — | EP | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ADH1A, ADH5, ADH1C | HDAC4 2021/4885ALDH1A1 7/4885KDM4E 1451/4885 |
| US-20140112946-A1 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2-DIHYDROQUINOLINE-3-CARBOXAMIDE | H1-5, MALT1, H1-4 | HDAC4 249/4885ALDH1A1 1885/4885KDM4E 154/4885 |
| US-20240277693-A1 | A PHARMACEUTICAL PRODUCT CONTAINING TASQUINIMOD AND A METHOD FOR ASSESSING THE PURITY OF SAID PRODUCT | TPMT, TLR7, MYD88 | HDAC4 1044/4885ALDH1A1 1211/4885KDM4E 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.