Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044899 | 0.93 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL1685962 | 0.88 | ALDH1A1 (0.65) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL39437 | 0.82 | EGFR (0.48) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL12009978 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL10044900 | 0.80 | CA12 (0.48) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL7598991 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL16079758 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL889415 | 0.78 | EGFR (0.51) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL2574422 | 0.76 | EGFR (0.47) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL19114816 | 0.76 | MEN1 (0.60) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590949-B1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| EP-2590949-B1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| US-8871936-B2 | Method for manufacturing of quinoline-3-carboxamides | ACTIVE BIOTECH AB (SE) | 2014-10-28 | — | — | US | disclosed |
| US-8871936-B2 | Method for manufacturing of quinoline-3-carboxamides | ACTIVE BIOTECH AB (SE) | 2014-10-28 | — | — | US | disclosed |
| US-8871936-B2 | Method for manufacturing of quinoline-3-carboxamides | ACTIVE BIOTECH AB (SE) | 2014-10-28 | — | — | US | disclosed |
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2013-05-02 | — | — | US | disclosed |
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2013-05-02 | — | — | US | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109860-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ADH1A, ADH5, ADH1C | ALDH1A1 7/4885KDM4E 1451/4885LMNA 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.