SCHEMBL10044933

SCHEMBL10044933

c1cnc(N2COc3ccncc3C2)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
AHR P35869 2/20 0.36
OGA O60502 3/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10044932 0.84 GRIN2D (0.47) CA12CA1CA2CA9AHR
SCHEMBL10311113 0.81 EED (0.41) RIPK1CA12CA1CA2CA9
SCHEMBL10045016 0.81 EED (0.42) RIPK1AHRMAPTPDE3BPDE3A
SCHEMBL10045015 0.80 CHRNB2 (0.42)
SCHEMBL16975586 0.76 KDM4E (0.40) RIPK1OGACYP1A2CYP2D6CYP2C19
SCHEMBL14295940 0.75 MAPK10 (0.33) CA12CA1CA2CA9CYP1A2
SCHEMBL10311126 0.72 MAPT (0.37) OGALMNAMAPTCYP1A2CYP2D6
SCHEMBL10044962 0.72 LMNA (0.37) OGALMNAMAPTCYP1A2CYP2D6
SCHEMBL765717 0.72 GAA (0.38) OGALMNAMAPTCYP1A2CYP2D6
SCHEMBL19114101 0.72 RIPK1 (0.33) RIPK1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355284-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-16 US disclosed
US-9515341-B2 Porous membrane, electrolyte membrane including same, methods of manufacturing both, and fuel cell including at least one of the membranes SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-06 US disclosed
US-9515341-B2 Porous membrane, electrolyte membrane including same, methods of manufacturing both, and fuel cell including at least one of the membranes SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-06 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-9368803-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-9368803-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-9178218-B2 Hyper-branched polymer, electrode and electrolyte membrane including the hyper-branched polymer, and fuel cell including at least one of the electrode and the electrolyte membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-9178218-B2 Hyper-branched polymer, electrode and electrolyte membrane including the hyper-branched polymer, and fuel cell including at least one of the electrode and the electrolyte membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-9096725-B2 Cross-linked polyazole, method of preparing the polyazole, electrode for fuel cell including the cross-linked polyazole, electrolyte membrane for fuel cell including the cross-linked polyazole, method of manufacturing the electrolyte membrane, and fuel cell including the cross-linked polyazole SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-04 US disclosed
US-20110189584-A1 POLYMER AND CROSS-LINKED POLYMER COMPOSITION, ELECTRODE AND ELECTROLYTE MEMBRANE INCLUDING CROSS-LINKED POLYMER, AND FUEL CELL INCLUDING ELECTRODE AND ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-04 US disclosed
US-20110189584-A1 POLYMER AND CROSS-LINKED POLYMER COMPOSITION, ELECTRODE AND ELECTROLYTE MEMBRANE INCLUDING CROSS-LINKED POLYMER, AND FUEL CELL INCLUDING ELECTRODE AND ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-04 US disclosed
US-20110189581-A1 COMPOUND, CROSS-LINKED MATERIAL THEREOF, DOUBLE CROSS-LINKED POLYMER THEREOF, AND ELECTROLYTE MEMBRANE, ELECTRODE FOR FUEL CELL AND FUEL CELL INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-04 US disclosed
US-20100273087-A1 CROSS-LINKED POLYAZOLE, METHOD OF PREPARING THE POLYAZOLE, ELECTRODE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, METHOD OF MANUFACTURING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-10-28 US disclosed
US-20100273087-A1 CROSS-LINKED POLYAZOLE, METHOD OF PREPARING THE POLYAZOLE, ELECTRODE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, METHOD OF MANUFACTURING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-10-28 US disclosed
US-20100159347-A1 HYPER-BRANCHED POLYMER, ELECTRODE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-24 US disclosed
US-20100159347-A1 HYPER-BRANCHED POLYMER, ELECTRODE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-24 US disclosed
US-20090075148-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-03-19 US disclosed
US-20090075148-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-03-19 US disclosed
EP-2036910-A1 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the same, electrolyte membrane for fuel cell includind the same, and fuel cell using the same Samsung Electronics Co., Ltd. (KR) 2009-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090075148-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE SAME, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE SAME, AND FUEL CELL USING THE SAME HCN1, KCNJ1, SQOR RIPK1 2607/4885CA12 396/4885CA1 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.