Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944828 | 0.86 | MMP8 (0.35) | PTPN1PTPN6PTPN11KDM4EKMT2A | |
| SCHEMBL10045693 | 0.83 | MEN1 (0.46) | PTPN1PTPN6PTPN11KDM4EKMT2A | |
| SCHEMBL2286242 | 0.71 | CYP4F2 (0.61) | KDM4EKMT2ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL10958880 | 0.70 | NR1D1 (0.51) | PTPN1PTPN6PTPN11KDM4EKMT2A | |
| SCHEMBL9054540 | 0.69 | EPHX2 (0.53) | CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL597578 | 0.68 | IDO1 (0.52) | KMT2ACYP4F2CYP4A11ALDH1A1MAPT | |
| SCHEMBL1996221 | 0.68 | MEN1 (0.41) | KDM4EKMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL20852089 | 0.68 | LPAR1 (0.48) | KMT2AALDH1A1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4241630 | 0.67 | ALDH1A1 (0.49) | PTPN1PTPN6PTPN11KDM4EKMT2A | |
| SCHEMBL14839655 | 0.66 | ACHE (0.49) | KDM4EKMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012627-A1 | METHOD OF PREVENTING OR TREATING VIRAL INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-01-26 | — | — | WO | disclosed |