Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805297 | 0.81 | ALDH1A1 (0.53) | ACHEBCHEALDH1A1LMNAKDM4E | |
| SCHEMBL17083311 | 0.80 | PYCR1 (0.50) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL22815158 | 0.80 | LTA4H (0.36) | ACHEBCHELTA4HPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL14798880 | 0.80 | ALDH1A1 (0.51) | ACHEBCHEALDH1A1LMNAKDM4E | |
| SCHEMBL304452 | 0.80 | RAB9A (0.55) | ACHEBCHEALDH1A1LTA4HMEN1 | |
| SCHEMBL16590371 | 0.79 | KMT2A (0.57) | ALDH1A1LTA4HMEN1KMT2AMAPT | |
| SCHEMBL14831985 | 0.79 | LTA4H (0.47) | ACHEBCHELTA4HMEN1KMT2A | |
| Potassium SCHEMBL6997235 | 0.78 | RAB9A (0.53) | ACHEBCHEALDH1A1LTA4HMEN1 | |
| Hydrochloric Acid SCHEMBL5760483 | 0.78 | RAB9A (0.53) | ACHEBCHEALDH1A1LTA4HMEN1 | |
| SCHEMBL17083316 | 0.77 | TAAR1 (0.58) | ALDH1A1LTA4HLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760838-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-05-10 | — | — | EP | disclosed |
| WO-2013045280-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-04-04 | — | — | WO | disclosed |