SCHEMBL10046313

SCHEMBL10046313

Nc1c(C(=O)O)cc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.56
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPK1 P28482 3/20 0.46
MAPT P10636 3/20 0.46
THRB P10828 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MCL1 Q07820 2/20 0.46
USP2 O75604 1/20 0.46
PKM P14618 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
TYMS P04818 1/20 0.45
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701776 0.88 HKDC1 (0.44) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL14701820 0.85 HKDC1 (0.43) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL12179670 0.84 HKDC1 (0.42) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL14701827 0.84 HKDC1 (0.40) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL14701788 0.83 MYC (0.43) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL12179577 0.82 HNF4A (0.46) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL14140057 0.78 TYMS (0.38) HKDC1MEN1KMT2AMAPK1MAPT
SCHEMBL1560856 0.74 MCL1 (0.52) MEN1KMT2AMAPK1KDM4EMCL1
SCHEMBL2179040 0.74 HSD17B10 (0.53) MAPTKDM4EMCL1CRHBPCRHR2
SCHEMBL9698148 0.73 ALDH1A1 (0.41) HKDC1MEN1KMT2AMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139417-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2021-05-13 US disclosed
EP-2665691-B1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2020-02-12 EP disclosed
US-9461260-B2 Organic light emitting device CANON KABUSHIKI KAISHA (JP) 2016-10-04 US disclosed
US-9315460-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9240554-B2 Organic compound, organic electroluminescence element, and image display device CANON KABUSHIKI KAISHA (JP) 2016-01-19 US disclosed
EP-2421809-B1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KK (JP) 2015-09-02 EP disclosed
US-9005778-B2 Organic compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
US-8968889-B2 Organic compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2015-03-03 US disclosed
US-8952873-B2 Fused polycyclic compound and organic light-emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2015-02-10 US disclosed
US-8940413-B2 Organic compound having acenaphtho[1,2-k]benzo[e]acephenanthrene derivative, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2015-01-27 US disclosed
US-8293384-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2012-10-23 US disclosed
US-8293384-B2 Organic compound, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2012-10-23 US disclosed
EP-2243761-B1 Phenanthrene derivatives, light-emitting device and image display apparatus using the same CANON KK (JP) 2012-08-22 EP disclosed
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed
WO-2011136155-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-11-03 WO disclosed
WO-2011121935-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-10-06 WO disclosed
US-20100270914-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-10-28 US disclosed
US-20100270914-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-10-28 US disclosed
WO-2010123153-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-10-28 WO disclosed
EP-2243761-A1 Phenanthrene derivatives, light-emitting device and image display apparatus using the same Canon Kabushiki Kaisha (JP) 2010-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS ACE, ACE2, AGTR1 HKDC1 2476/4885MEN1 3665/4885KMT2A 2118/4885
US-20210139417-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CYP1A1, POU2F1, NFE2L2 HKDC1 4274/4885MEN1 1249/4885KMT2A 2083/4885
US-20100270914-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS ACE2, ACE, AGTR1 HKDC1 1317/4885MEN1 3023/4885KMT2A 1642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.