Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046376 | 0.78 | PDGFRB (0.38) | NPC1RAB9ABRD4ADORA1LMNA | |
| SCHEMBL10046380 | 0.77 | NPC1 (0.34) | NPC1KDM4EMAPTRAB9A | |
| SCHEMBL10046382 | 0.74 | PDE10A (0.37) | NPC1KDM4EMAPTRAB9ALMNA | |
| SCHEMBL10046377 | 0.72 | HPGDS (0.48) | PDE10A | |
| SCHEMBL10046378 | 0.70 | TDO2 (0.39) | NPC1KDM4EMAPTRAB9AADORA1 | |
| SCHEMBL9892687 | 0.68 | TYR (0.40) | NPC1KDM4EMAPTRAB9ATUBB4A | |
| SCHEMBL26260066 | 0.67 | HIF1A (0.43) | KDRTLR9TLR8TLR7KDM4E | |
| SCHEMBL10046375 | 0.64 | PLAU (0.42) | KDRMAPTBRD4 | |
| SCHEMBL13074830 | 0.64 | HTR6 (0.39) | KDRTACR3KDM4ETUBB4ATUBB | |
| SCHEMBL10099091 | 0.63 | MAPT (0.56) | KDM4EMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165534-A1 | PROCESS FOR PREPARING BROMO-SUBSTITUTED QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165534-A1 | PROCESS FOR PREPARING BROMO-SUBSTITUTED QUINOLINES | HCCS, CYP3A7, ABL1 | KDR 3772/4885TLR9 3557/4885TLR8 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.