Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892705 | 0.86 | CYP19A1 (0.42) | PDE10APIK3CDPIK3CAPIK3CGNPC1 | |
| SCHEMBL10046378 | 0.78 | TDO2 (0.39) | PDE10ANPC1RAB9AKDM4ELMNA | |
| SCHEMBL10046380 | 0.76 | NPC1 (0.34) | NPC1RAB9AKDM4EMAPTLRRK2 | |
| SCHEMBL10046381 | 0.74 | KDR (0.34) | PDE10ANPC1RAB9AKDM4ELMNA | |
| SCHEMBL10046376 | 0.74 | PDGFRB (0.38) | PDE10APIK3CGNPC1RAB9ALMNA | |
| SCHEMBL9892687 | 0.74 | TYR (0.40) | NPC1RAB9AKDM4ELMNAMAPT | |
| SCHEMBL26260088 | 0.72 | HIF1A (0.41) | PDE10APIK3CDPIK3CAPIK3CGNPC1 | |
| SCHEMBL10046377 | 0.71 | HPGDS (0.48) | PDE10AIDO1TDO2 | |
| SCHEMBL27945885 | 0.68 | PIK3CD (0.43) | PDE10APIK3CDPIK3CAPIK3CGNPC1 | |
| SCHEMBL27258890 | 0.66 | ESR1 (0.45) | PDE10APIK3CDPIK3CAPIK3CGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165534-A1 | PROCESS FOR PREPARING BROMO-SUBSTITUTED QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165534-A1 | PROCESS FOR PREPARING BROMO-SUBSTITUTED QUINOLINES | HCCS, CYP3A7, ABL1 | PDE10A 3910/4885PIK3CD 3265/4885PIK3CA 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.