Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046382 | 0.86 | PDE10A (0.37) | CYP19A1CYP11B1CYP11B2PDE10ABDKRB2 | |
| SCHEMBL7909715 | 0.77 | HTR6 (0.39) | CYP19A1CYP11B1CYP11B2PDE10APIK3CA | |
| SCHEMBL9892707 | 0.77 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2PDE10AMAPT | |
| SCHEMBL10046375 | 0.74 | PLAU (0.42) | CYP19A1CYP11B1CYP11B2PIK3CDPIK3CA | |
| SCHEMBL10046379 | 0.74 | TRIM33 (0.39) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL9892685 | 0.73 | TYR (0.40) | MAPTNPC1KDM4ELMNARAB9A | |
| SCHEMBL9892684 | 0.69 | ALDH1A1 (0.46) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL26260088 | 0.68 | HIF1A (0.41) | PDE10APIK3CDPIK3CAPIK3CGMAPT | |
| SCHEMBL27945885 | 0.67 | PIK3CD (0.43) | PDE10APIK3CDPIK3CAPIK3CGMAPT | |
| SCHEMBL10046378 | 0.65 | TDO2 (0.39) | PDE10AMAPTNPC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | GYS2, CYP3A7, GBA1 | CYP19A1 556/4885CYP11B1 296/4885CYP11B2 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.