Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343965 | 0.86 | PTGS2 (0.36) | KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL11451849 | 0.79 | KDM4E (0.44) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL11940428 | 0.77 | CES2 (0.49) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL6167985 | 0.76 | MAPT (0.42) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL11982327 | 0.73 | PIM1 (0.40) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL29571711 | 0.70 | ALDH1A1 (0.50) | MAPTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL11964019 | 0.69 | TSHR (0.44) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL15775854 | 0.66 | ALDH1A1 (0.37) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL7760470 | 0.65 | KDM4E (0.40) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL9769490 | 0.65 | KDM4E (0.40) | MAPTKMT2AALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892550-B | 4-phenyl-6H-1, 3-oxazine-6-one derivatives, preparation and application thereof | 苏州大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-111892550-A | 4-phenyl-6H-1, 3-oxazine-6-one derivatives, preparation and application thereof | 苏州大学 | 2020-11-06 | — | — | CN | disclosed |
| US-8846955-B2 | Second-order nonlinear optical compound and nonlinear optical element comprising the same | NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) | 2014-09-30 | — | — | US | disclosed |
| EP-2126625-B1 | SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE | NITTO DENKO CORP (JP) | 2012-02-22 | — | — | EP | disclosed |
| WO-2011024774-A1 | SECOND-ORDER NON-LINEAR OPTICAL COMPOUND AND NON-LINEAR OPTICAL ELEMENT COMPRISING SAME | 独立行政法人情報通信研究機構 (JP) | 2011-03-03 | — | — | WO | disclosed |
| EP-2261270-A1 | Polymer, producing method thereof, and photorefractive composition | Nitto Denko Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |
| US-20090092746-A1 | PHOTOREFRACTIVE COMPOSITIONS WITH NANOPARTICLES | NITTO DENKO CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20090092746-A1 | PHOTOREFRACTIVE COMPOSITIONS WITH NANOPARTICLES | NITTO DENKO CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-4284787-A | Process for the preparation of 1,2,3-triazoles substituted in the 2-position | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| EP-0004897-B1 | PROCESS FOR THE PREPARATION OF 1,2,3 TRIAZOLES SUBSTITUTED IN THE 2-POSITION | BAYER AG (DE) | 1981-03-18 | — | — | EP | disclosed |
| EP-0004897-A2 | Process for the preparation of 1,2,3 triazoles substituted in the 2-position | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |