Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760470 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL8013801 | 0.83 | PDE3B (0.41) | ALDH1A1MAPTKMT2AHPGDHSD17B10 | |
| SCHEMBL41171 | 0.76 | RAB9A (0.47) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL4649359 | 0.73 | PDE3B (0.71) | PDE3BPDE3AGPR119 | |
| SCHEMBL11740987 | 0.72 | CYP2D6 (0.38) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL3290342 | 0.70 | RAB9A (0.42) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL11738724 | 0.69 | MAOB (0.40) | KDM4EALDH1A1MAPTKMT2AGAA | |
| Carbamic Acid SCHEMBL6809303 | 0.69 | RAB9A (0.45) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL24756807 | 0.69 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTKMT2AGAA | |
| SCHEMBL23712435 | 0.67 | DGAT1 (0.75) | ESR1ESR2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011943-A | FK-506 C10 -C24 process intermediates | MERCK FROSST CANADA, INC. (CA) | 1991-04-30 | — | — | US | disclosed |