Homosalate

Homosalate

SCHEMBL1004720

CC1CC(OC(=O)c2ccccc2O)CC(C)(C)C1.COc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.68
ALDH1A1 P00352 4/20 0.68
CYP1A2 P05177 3/20 0.68
CYP2C19 P33261 3/20 0.68
CYP3A4 P08684 3/20 0.68
CYP2C9 P11712 1/20 0.68
HPGD P15428 5/20 0.57
PGR P06401 2/20 0.57
SLC6A2 P23975 2/20 0.57
HTT P42858 2/20 0.57
CYP2D6 P10635 1/20 0.57
PDE4A P27815 1/20 0.57
MAPK1 P28482 1/20 0.57
HRH1 P35367 1/20 0.57
SLC6A3 Q01959 1/20 0.57
PDE4D Q08499 1/20 0.57
ADORA3 P0DMS8 1/20 0.52
AR P10275 1/20 0.52
CHRM1 P11229 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homosalate SCHEMBL2016281 0.87 LMNA (0.86) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL2808104 0.84 ALDH1A1 (0.97) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL8106557 0.83 LMNA (0.86) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL8840156 0.83 ALDH1A1 (0.86) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL3634890 0.82 ALDH1A1 (1.00) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL16207 0.82 ALDH1A1 (1.00) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL29356436 0.82 ALDH1A1 (1.00) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Homosalate SCHEMBL8863191 0.82 LMNA (0.84) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Oxybenzone SCHEMBL28230340 0.79 HPGD (0.91) LMNAALDH1A1CYP1A2CYP2C19CYP3A4
Dioxybenzone SCHEMBL5161579 0.78 HPGD (0.88) LMNAALDH1A1CYP1A2CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012000674-A1 TOPICAL COMPOSITION FOR THE TREATMENT OF SCAR TISSUE SYLPHAR (BE) 2012-01-05 WO claimed
WO-2024102219-A1 COMPOSITIONS INCLUDING CAFFEIC ACID PHENETHYL ESTER XMK THERAPEUTICS INC. (CA) 2024-05-16 WO disclosed
US-10743604-B2 Articles of manufacture releasing an active ingredient NNTT TECH INC. (CA) 2020-08-18 US disclosed
EP-3434264-A1 MICROPARTICLE FOR RELEASING AN ACITVE AGENT Biomod Concepts Inc. (CA) 2019-01-30 EP disclosed
EP-2317984-B1 ARTICLES OF MANUFACTURE RELEASING AN ACTIVE INGREDIENT BIOMOD CONCEPTS INC (CA) 2018-10-31 EP disclosed
US-20180146735-A1 Articles Of Manufacture Releasing An Active Ingredient NNTT TECH INC. (CA) 2018-05-31 US disclosed
US-9883710-B2 Articles of manufacture releasing an active ingredient BIOMOD CONCEPTS INC. (CA) 2018-02-06 US disclosed
US-9861154-B2 Articles of manufacture releasing an active ingredient BIOMOD COLLECTION INC. (CA) 2018-01-09 US disclosed
US-9730483-B2 Articles of manufacture releasing an active ingredient BIOMOD CONCEPTS INC. (CA) 2017-08-15 US disclosed
CN-102099015-B Articles of manufacture releasing an active ingredient BIOMOD CONCEPTS INC 2015-05-06 CN disclosed
US-20030232094-A1 Composition and method for the treatment of skin irritations FULLER PETER E (US) 2003-12-18 US disclosed
EP-1251818-A1 GALENIC FORMULATION MERCK PATENT GmbH (DE) 2002-10-30 EP disclosed
CN-1353735-A Silicone gel containing salicylic acid NEUTROGENA CORP (US) 2002-06-12 CN disclosed
US-6384023-B2 SKIN DISORDERS; ACNE, SEBORRHEA NEUTROGENA CORPORATION 2002-05-07 US disclosed
EP-1181329-A1 SILICONE GEL CONTAINING SALICYLIC ACID NEUTROGENA CORPORATION (US) 2002-02-27 EP disclosed
US-20010018432-A1 Silicone gel containing salicylic acid JOHNSON & JOHNSON CONSUMER INC. 2001-08-30 US disclosed
WO-2001054653-A1 GALENIC FORMULATION MERCK PATENT GMBH (DE) 2001-08-02 WO disclosed
US-6200964-B1 FOR PREVENTION AND TREATMENT OF ACNE OR SEBORRHEA NEUTROGENA CORPORATION 2001-03-13 US disclosed
WO-2000073374-A1 SILICONE GEL CONTAINING SALICYLIC ACID NEUTROGENA CORPORATION (US) 2000-12-07 WO disclosed
WO-2000072817-A1 WATER-IN-OIL EMULSION COMPRISING A SILICONE GEL CONTAINING VITAMIN C NEUTROGENA CORPORATION (US) 2000-12-07 WO disclosed