Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 6/20 | 0.41 |
| ▸ | RXRB | P28702 | 6/20 | 0.41 |
| ▸ | RXRG | P48443 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811873 | 0.80 | LMNA (0.59) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL18903119 | 0.75 | HRH3 (0.48) | ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL19039266 | 0.75 | NISCH (0.36) | GAAALDH1A1POLBKDM4ETDP1 | |
| SCHEMBL11834588 | 0.75 | — | — | |
| SCHEMBL10116847 | 0.73 | — | — | |
| SCHEMBL18427891 | 0.73 | LMNA (0.86) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL68027 | 0.73 | LMNA (0.86) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL11857930 | 0.72 | ACMSD (0.54) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL11861303 | 0.72 | ABCC4 (0.53) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL18306856 | 0.72 | ESR1 (0.42) | LMNACA2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093028-B2 | Engineered glycosyltransferases with expanded substrate specificity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-01-10 | — | — | US | disclosed |