Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRG | P48443 | 5/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861303 | 0.96 | ABCC4 (0.53) | ACMSDABCC4LMNAGAATSHR | |
| SCHEMBL9811873 | 0.87 | LMNA (0.59) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL11828541 | 0.80 | ACMSD (0.46) | ACMSDHDAC3HDAC1HDAC2FFAR1 | |
| SCHEMBL11826714 | 0.79 | ACMSD (0.45) | ACMSDHDAC3HDAC1HDAC2FFAR1 | |
| SCHEMBL10793933 | 0.78 | ACMSD (0.53) | ACMSDHDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL6069021 | 0.78 | ACMSD (0.61) | ACMSDTSHRRXRARXRBRXRG | |
| SCHEMBL25456721 | 0.78 | FFAR4 (0.56) | ACMSDHDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL11837209 | 0.78 | ACMSD (0.47) | ACMSDHDAC3HDAC1HDAC2FFAR1 | |
| SCHEMBL11856441 | 0.78 | CYP4Z1 (0.45) | ACMSDLMNATSHRHDAC1HDAC2 | |
| SCHEMBL11862219 | 0.77 | ACMSD (0.47) | ACMSDTSHRHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3944589-A | α-Cycloalkenylphenyl-fatty acid nitriles | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |