Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 6/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.50 |
| ▸ | RXRG | P48443 | 6/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861303 | 0.87 | ABCC4 (0.53) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL11857930 | 0.87 | ACMSD (0.54) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL10047635 | 0.80 | LMNA (0.50) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL68027 | 0.80 | LMNA (0.86) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL18427891 | 0.80 | LMNA (0.86) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL69614 | 0.78 | CA2 (0.79) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL27708959 | 0.76 | LMNA (0.59) | LMNAGAATSHRABCC4PTGS1 | |
| Hydrochloric Acid SCHEMBL25180348 | 0.75 | CA2 (0.75) | LMNAGAATSHRABCC4PTGS1 | |
| Hydrochloric Acid SCHEMBL6765874 | 0.75 | CA2 (0.75) | LMNAGAATSHRABCC4PTGS1 | |
| SCHEMBL9320716 | 0.74 | PTGS2 (0.41) | TSHRPTGS1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251357-B1 | ENGINEERING THERMOPLASTICS CONTAINING PENDANT BENZOCYCLOBUTENE GROUPS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-07-17 | — | — | EP | disclosed |
| EP-0251357-A1 | Engineering thermoplastics containing pendant benzocyclobutene groups | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-01-07 | — | — | EP | disclosed |
| US-4708994-A | CURING, CROSSLINKING; SOLVENT RESISTANCE | SHELL OIL COMPANY (US) | 1987-11-24 | — | — | US | disclosed |