SCHEMBL1004778

SCHEMBL1004778

CCc1cccc(Br)c1O

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.70
GABRB2 P47870 4/20 0.70
CA2 P00918 1/20 0.46
ACHE P22303 1/20 0.46
EGFR P00533 5/20 0.44
ERBB2 P04626 4/20 0.42
RIPK1 Q13546 1/20 0.42
IAPP P10997 3/20 0.39
ALOX5 P09917 1/20 0.38
PTGS2 P35354 1/20 0.38
TTR P02766 1/20 0.38
PTPN5 P54829 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL199730 0.83 GABRA1 (1.00) GABRA1GABRB2CA2IAPPPTPN5
SCHEMBL16788658 0.83 ALOX5 (0.47) GABRA1GABRB2CA2ACHEEGFR
SCHEMBL8406789 0.82 GABRA1 (0.52) GABRA1GABRB2CA2ACHEEGFR
SCHEMBL27561169 0.81 GABRA1 (0.45) GABRA1GABRB2CA2ACHEEGFR
SCHEMBL11164405 0.79 ALOX5 (0.57) GABRA1GABRB2EGFRERBB2IAPP
SCHEMBL1450337 0.79 CA2 (0.44) GABRA1GABRB2CA2ACHEEGFR
SCHEMBL17916374 0.79 GABRA1 (0.52) GABRA1GABRB2CA2RIPK1TSHR
SCHEMBL28161012 0.79 CA2 (0.44) GABRA1GABRB2CA2ACHEEGFR
Water SCHEMBL28947715 0.78 GABRA1 (0.90) GABRA1GABRB2IAPPPTPN5
Alcohol SCHEMBL28268569 0.78 GABRA1 (0.90) GABRA1GABRB2IAPPALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015459-A1 Method for synthesizing polyphenylene ether Chem Tech Solutions, LLC (US) 2026-01-15 US claimed
CN-119875110-A Polyphenylene ether, polyphenylene ether solution, resin film, prepreg, and metal-clad laminate 旭化成株式会社 2025-04-25 CN claimed
CN-119101232-B Method and reaction device for on-line control of molecular weight of polyphenyl ether product 上海优铖工逸技术有限公司 2025-03-14 CN claimed
CN-119101232-A Method and reaction device for on-line control of molecular weight of polyphenyl ether product 上海优铖工逸技术有限公司 2024-12-10 CN claimed
CN-114736367-A Green and safe polyarylether gas-liquid heterogeneous synthesis method 常州中英科技股份有限公司 2022-07-12 CN claimed
CN-114716666-A Polyarylether synthesis method based on gas-liquid heterogeneous phase method and continuous flow microchannel reactor 常州中英科技股份有限公司 2022-07-08 CN claimed
CN-108641077-B Synthetic method of polyphenyl ether 广东省石油与精细化工研究院 2020-07-28 CN claimed
EP-4695235-A1 NOVEL GSPT1 DEGRADER AND USE THEREOF Cyrus Therapeutics Inc. (KR) 2026-02-18 EP disclosed
US-20260015459-A1 Method for synthesizing polyphenylene ether Chem Tech Solutions, LLC (US) 2026-01-15 US disclosed
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4282899-B1 POLYPHENYLENE ETHER, PRODUCTION METHOD, THERMOSETTING COMPOSITION, PREPREG, AND LAMINATE THEREOF ASAHI CHEMICAL IND (JP) 2025-07-16 EP disclosed
WO-2025127084-A1 RUBBER COMPOSITION AND METHOD FOR USING POLYPHENYLENE ETHER 旭化成株式会社 2025-06-19 WO disclosed
EP-4342930-B1 POLYPHENYLENE ETHER, PRODUCTION METHOD THEREFOR, THERMOSETTING COMPOSITION, PREPREG, AND MULTILAYER BODY ASAHI CHEMICAL IND (JP) 2025-06-11 EP disclosed
CN-87107289-A The production method of polyphenylene oxide 1988-06-15 CN disclosed
EP-0132608-B1 PROCESS FOR THE POLYMERIZATION OF A 2,6-DISUBSTITUTED PHENOL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-03-09 EP disclosed
US-4558119-A WITH MANGANESE COMPOUND, N-ALKYLALKANOLAMINE, AND A BASIC COMPOUNDCATALYTIC MIXTURE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
US-4532367-A Antimicrobially effective derivatives of phenol and methods for their production VEB JENAPHARM (DD) 1985-07-30 US disclosed
EP-0132608-A1 Process for the polymerization of a 2,6-disubstituted phenol Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-02-13 EP disclosed
EP-0069374-A2 Phenolic compounds, process for their preparation and pharmaceutical compositions containing them JENAPHARM GmbH (DE) 1983-01-12 EP disclosed
US-4001426-A HAVING CORONARY VASODILATOR ACTIVITY SMITHKLINE CORPORATION (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015459-A1 Method for synthesizing polyphenylene ether CYP2E1, HPD, ELL GABRA1 3406/4885GABRB2 3243/4885CA2 3993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.