Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557019 | 0.82 | CA2 (0.41) | CA2ACHEGABRA1GABRB2EGFR | |
| SCHEMBL196227 | 0.82 | GABRA1 (0.57) | CA2GABRA1GABRB2APOBEC3GEGFR | |
| SCHEMBL1004778 | 0.79 | GABRA1 (0.70) | CA2ACHEGABRA1GABRB2EGFR | |
| SCHEMBL9715113 | 0.79 | PARP1 (0.36) | KDM4ELMNATP53MAPTTSHR | |
| SCHEMBL608328 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2APOBEC3GTAAR1PDCD1 | |
| SCHEMBL6942317 | 0.78 | APOBEC3G (0.39) | CA2GABRA1GABRB2APOBEC3GTAAR1 | |
| Hydrochloric Acid SCHEMBL25305592 | 0.77 | CA2 (0.45) | CA2ACHEGABRA1GABRB2EGFR | |
| SCHEMBL110893 | 0.77 | — | — | |
| SCHEMBL2116718 | 0.76 | PARP1 (0.41) | GABRA1GABRB2APOBEC3GTAAR1PDCD1 | |
| SCHEMBL29790993 | 0.76 | APOBEC3G (0.38) | GABRA1GABRB2APOBEC3GTAAR1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552791-B2 | Heterocyclic GLP-1 agonists | GASHERBRUM BIO, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| EP-4143183-B1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO INC (US) | 2025-10-22 | — | — | EP | disclosed |
| US-20250214999-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHOUTI INC. | 2025-07-03 | — | — | US | disclosed |
| CN-118530083-A | Novel method for selectively removing bromine atoms on aromatic ring | 嘉兴学院 | 2024-08-23 | — | — | CN | disclosed |
| WO-2024129896-A1 | INHIBITORS OF PROCASPASE-6 ACTIVATION AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-06-20 | — | — | WO | disclosed |
| US-20230295154-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHOUTI INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230295154-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHOUTI INC. | 2023-09-21 | — | — | US | disclosed |
| EP-4143183-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115667250-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2011121002-A1 | HYDROXYLATED PHOSPHORYLATED CONTRAST ENHANCEMENT AGENTS | GENERAL ELECTRIC COMPANY (US) | 2011-10-06 | — | — | WO | disclosed |
| US-7910018-B2 | Compounds for use in liquid crystal devices | QINETIQ LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-20090066905-A1 | Componds for use in liquid crystal devices | QINETIQ LIMITED (GB) | 2009-03-12 | — | — | US | disclosed |
| EP-1814870-A2 | BENZO-1,3-DIOXANES FOR USE IN LIQUID CRYSTAL DEVICES | Qinetiq Limited (GB) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006048620-A2 | BENZO-1, 3-DIOXANES FOR USE IN LIQUID CRYSTAL DEVICES | QINETIQ LIMITED (GB) | 2006-05-11 | — | — | WO | disclosed |
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1394147-A1 | CARBOXYLIC ACID DERIVATIVE AND MEDICINE COMPRISING SALT OR ESTER OF THE SAME | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295154-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | CA2 2913/4885ACHE 2378/4885GABRA1 884/4885 |
| US-20090066905-A1 | Componds for use in liquid crystal devices | FZD7, CFD, PYCARD | CA2 1277/4885ACHE 1728/4885GABRA1 4667/4885 |
| US-12552791-B2 | Heterocyclic GLP-1 agonists | GLP1R, NPY1R, NPY2R | CA2 222/4885ACHE 3336/4885GABRA1 505/4885 |
| US-20250214999-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | CA2 2913/4885ACHE 2378/4885GABRA1 884/4885 |
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | GPR119, NR3C1, INSR | CA2 525/4885ACHE 4721/4885GABRA1 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.