SCHEMBL1004827

SCHEMBL1004827

C=Cc1ccccc1COC(N)=S.NC(O)=S

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
PKM P14618 1/20 0.32
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8722929 0.81 ALDH1A1 (0.35) ALDH1A1CA12CA1CA2CA9
SCHEMBL5143591 0.74 PPARG (0.56) ALDH1A1GAAPKM
SCHEMBL2963707 0.74 KMT2A (0.38) ALDH1A1GAACA12CA1CA2
SCHEMBL61037 0.73 ALDH1A1 (0.50) ALDH1A1PKM
SCHEMBL2029842 0.73 THRB (0.46) ALDH1A1
SCHEMBL252296 0.73 ALDH1A1 (0.43) ALDH1A1IDO1
Phenol SCHEMBL9818392 0.73 TDP1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL2773503 0.71 CA12 (0.59) ALDH1A1CA12CA1CA2CA9
Benzene SCHEMBL29116606 0.71 CA12 (0.59) ALDH1A1CA12CA1CA2CA9
SCHEMBL10775904 0.71 ALDH1A1 (0.36) ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964692-B2 Polymer obtained by addition-polymerization initiated by a silicon compound JNC CORPORATION (JP) 2011-06-21 US claimed
US-7863396-B2 Silicon compounds CHISSO CORPORATION (JP) 2011-01-04 US claimed
US-11912952-B2 Material and sliding system KYOTO UNIVERSITY (JP) 2024-02-27 US disclosed
EP-3438231-B1 MATERIAL FOR SLIDE MECHANISMS COMPRISING A POLYMER BRUSH UNIV KYOTO (JP) 2023-08-02 EP disclosed
US-20230034470-A1 MATERIAL AND SLIDING SYSTEM National Institute of Technology (JP) 2023-02-02 US disclosed
US-11168170-B2 Clearance narrowing material, clearance narrowing material composite, and article using same KYOTO UNIVERSITY (JP) 2021-11-09 US disclosed
US-20200181309-A1 CLEARANCE NARROWING MATERIAL, CLEARANCE NARROWING MATERIAL COMPOSITE, AND ARTICLE USING SAME KYOTO UNIVERSITY (JP) 2020-06-11 US disclosed
US-20190119596-A1 LUBRICANT AND SRT MATERIAL KYOTO UNIVERSITY (JP) 2019-04-25 US disclosed
EP-3438231-A1 LUBRICANT AND SRT MATERIAL Kyoto University (JP) 2019-02-06 EP disclosed
EP-1548020-B1 SILICON COMPOUND JNC CORP (JP) 2014-07-23 EP disclosed
US-8293442-B2 Resin particle, toner, and image forming method and process cartridge using the same RICOH COMPANY, LTD. (JP) 2012-10-23 US disclosed
US-20060175684-A1 Organosilicon compound JNC PETROCHEMICAL CORPORATION (JP) 2006-08-10 US disclosed
EP-1686133-A2 Organosilicon compound CHISSO CORPORATION (JP) 2006-08-02 EP disclosed
US-20060094849-A1 Silicon compound JNC CORPORATION (JP) 2006-05-04 US disclosed
EP-1650214-A2 Silicon compound CHISSO CORPORATION (JP) 2006-04-26 EP disclosed
US-20050288468-A1 Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers JNC CORPORATION (JP) 2005-12-29 US disclosed
US-20050250925-A1 Silicon compound JNC CORPORATION (JP) 2005-11-10 US disclosed
EP-1550664-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-07-06 EP disclosed
EP-1548020-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-06-29 EP disclosed
US-20050049381-A1 Silicon compounds YAMAHIRO MIKIO (JP) 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288468-A1 Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers STS, SULT1A1, SRM ALDH1A1 384/4885GAA 1726/4885CA12 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.