Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575296 | 0.78 | RXRA (0.47) | ALDH1A1SRD5A2PDE5AHPGDSMN1; SMN2 | |
| SCHEMBL13962632 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNASRD5A2HPGDCES2 | |
| SCHEMBL12962949 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNASRD5A2HPGDCES2 | |
| SCHEMBL14456579 | 0.74 | LMNA (0.31) | LMNA | |
| SCHEMBL6277324 | 0.71 | CYP2C9 (0.37) | ALDH1A1MAPTKMT2ATDP1CA1 | |
| SCHEMBL14201547 | 0.70 | RET (0.32) | — | |
| SCHEMBL18664681 | 0.69 | CYP2A6 (0.39) | ALDH1A1 | |
| SCHEMBL13522670 | 0.69 | HTT (0.43) | ALDH1A1LMNASRD5A2HPGDCES2 | |
| SCHEMBL13893312 | 0.68 | CYP2A6 (0.41) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL6900523 | 0.68 | ACHE (0.34) | MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084940-A1 | USE OF OLIGOMERS AS COMPATIBILIZERS FOR INORGANIC PARTICLES AND COMPOSITIONS CONTAINING COMPATIBILIZER, INORGANIC PARTICLES AND POLYMER | SOLVAY SA (BE) | 2012-06-28 | — | — | WO | disclosed |