Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30357987 | 0.74 | SMYD3 (0.56) | MTNR1AMTNR1BSMYD3DRD2 | |
| SCHEMBL5245111 | 0.74 | SMYD3 (0.56) | MTNR1AMTNR1BSMYD3DRD2 | |
| SCHEMBL10049487 | 0.74 | — | — | |
| SCHEMBL10049491 | 0.74 | PDE7A (0.37) | PDE7A | |
| SCHEMBL10049792 | 0.72 | PNMT (0.32) | PDE7A | |
| SCHEMBL5265048 | 0.68 | GAA (0.41) | SMYD3 | |
| SCHEMBL8129742 | 0.68 | GAA (0.41) | SMYD3DRD2 | |
| SCHEMBL30358013 | 0.67 | HTR1A (0.47) | MTNR1AMTNR1BDRD2 | |
| SCHEMBL4974159 | 0.67 | ACHE (0.38) | MTNR1AMTNR1BSMYD3 | |
| SCHEMBL7236537 | 0.66 | SMYD3 (0.44) | MTNR1AMTNR1BSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009369-A1 | CATALYSTS BASED ON QUINOLINE PRECURSORS | BASELL POLYOLEFINE GMBG (DE) | 2012-01-19 | — | — | WO | disclosed |