Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10049792 | 0.80 | PNMT (0.32) | PDE7A | |
| SCHEMBL10049492 | 0.74 | MTNR1A (0.35) | PDE7A | |
| SCHEMBL6575709 | 0.71 | MTNR1A (0.45) | — | |
| SCHEMBL2321700 | 0.71 | LMNA (0.36) | — | |
| SCHEMBL652655 | 0.68 | PARP10 (0.43) | PDE7A | |
| SCHEMBL21676033 | 0.67 | DRD1 (0.43) | — | |
| SCHEMBL31402653 | 0.67 | P2RX7 (0.35) | — | |
| SCHEMBL6796232 | 0.65 | SRC (0.49) | PDE7ACA12CA1CA2CA9 | |
| SCHEMBL23043336 | 0.64 | P2RX7 (0.36) | — | |
| SCHEMBL6090116 | 0.64 | NPC1 (0.50) | PDE7ACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009369-A1 | CATALYSTS BASED ON QUINOLINE PRECURSORS | BASELL POLYOLEFINE GMBG (DE) | 2012-01-19 | — | — | WO | disclosed |