SCHEMBL1004955

SCHEMBL1004955

COC(=O)c1cc(I)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.67
CA1 P00915 5/20 0.67
CA2 P00918 5/20 0.67
CA7 P43166 5/20 0.67
CA9 Q16790 5/20 0.67
CA14 Q9ULX7 5/20 0.67
LMNA P02545 2/20 0.55
TSHR P16473 1/20 0.55
PTGS2 P35354 1/20 0.54
PDK2 Q15119 1/20 0.52
PDK4 Q16654 1/20 0.52
GAA P10253 1/20 0.49
XDH P47989 1/20 0.48
AR P10275 2/20 0.48
EGFR P00533 3/20 0.48
NOX4 Q9NPH5 1/20 0.48
PTPN11 Q06124 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993089 0.85 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL256715 0.85 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL15326189 0.84 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL31585831 0.84 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL1277539 0.82 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL12240241 0.81 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL3895902 0.80 CA12 (0.70) CA12CA1CA2CA7CA9
SCHEMBL8067198 0.80 CA12 (0.70) CA12CA1CA2CA7CA9
SCHEMBL9600264 0.80 EGFR (0.50) CA12CA1CA2CA7CA9
Methyl 2,5-Dihydroxybenzoate SCHEMBL38890 0.80 CA12 (1.00) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102164-A1 COMPOSITIONS AND METHODS OF USE THEREOF BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-05-15 WO disclosed
CN-122010913-A Rhodamine-marked isoquinoline derivative and preparation method and application thereof 淮阴师范学院 2026-05-12 CN disclosed
US-12577469-B2 Compound, composition, cured product, optically anisotropic body, optical element, and light guide element FUJIFILM CORPORATION (JP) 2026-03-17 US disclosed
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels THE CLEVELAND CLINIC FOUNDATION (US) 2026-03-17 US disclosed
WO-2025059074-A1 BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION PMV PHARMACEUTICALS, INC. (US) 2025-03-20 WO disclosed
WO-2025013754-A1 COMPOUND, COMPOSITION, CURED PRODUCT, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT 富士フイルム株式会社 2025-01-16 WO disclosed
WO-2024243289-A2 GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE THE CLEVELAND CLINIC FOUNDATION (US) 2024-11-28 WO disclosed
WO-2024176696-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND POLYMER COMPOUND 東京応化工業株式会社 2024-08-29 WO disclosed
US-12054660-B2 Compound, composition, cured substance, optically anisotropic body, optical element, and light guide element FUJIFILM CORPORATION (JP) 2024-08-06 US disclosed
US-20240209263-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2024-06-27 US disclosed
US-5098930-A Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-03-24 US disclosed
US-5089513-A Antiinflammatory agents; antiallergens; asthma; side effect reduction ICI PHARMA (FR) 1992-02-18 US disclosed
US-5039511-A Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1991-08-13 US disclosed
US-5015661-A Lipoxygenase inhibitors HOFFMANN-LA ROCHE INC. (US) 1991-05-14 US disclosed
US-5008099-A Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1991-04-16 US disclosed
US-4959391-A LIPOXYGENASE INHIBITORS, LEUKOTRIENE DISEASES GRUENENTHAL GMBH (DE) 1990-09-25 US disclosed
EP-0375404-A2 Heterocyclic derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-27 EP disclosed
US-4933156-A Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1990-06-12 US disclosed
EP-0287909-A1 Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor SALUTAR, INC. (US) 1988-10-26 EP disclosed
US-4760087-A 5-lipoxygenase inhibitor GRUENENTHAL GMBH (DE) 1988-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12054660-B2 Compound, composition, cured substance, optically anisotropic body, optical element, and light guide element SP1, C5, ZYX CA12 339/4885CA1 132/4885CA2 1198/4885
US-12576055-B2 Disease detection and treatment based on trimethyl-lysine levels BHMT, BHMT2, EHMT2 CA12 1832/4885CA1 2402/4885CA2 1446/4885
US-12577469-B2 Compound, composition, cured product, optically anisotropic body, optical element, and light guide element CRY2, SCO2, CRY1 CA12 320/4885CA1 865/4885CA2 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.