SCHEMBL10050183

SCHEMBL10050183

CCc1c(C)c(C)c(C)c(CC)c1OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.36
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CA1 P00915 1/20 0.32
CA6 P23280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2956027 0.82 PTGS2 (0.42) PTGS2CA2CA4CA1CA6
SCHEMBL10751874 0.80 PTGS2 (0.31) PTGS2
SCHEMBL25328660 0.79 ALOX5 (0.34) PTGS2
SCHEMBL25330017 0.75 IMPDH2 (0.38) PTGS2
SCHEMBL9345546 0.75 GAA (0.31)
SCHEMBL9345587 0.75 GAA (0.31)
SCHEMBL25328865 0.74 ALOX5 (0.37) PTGS2CA2CA4
SCHEMBL10749887 0.74 PTGS2 (0.43) PTGS2CA2CA4CA1CA6
SCHEMBL32689518 0.74 IMPDH2 (0.41)
SCHEMBL21602868 0.74 IMPDH2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8734693-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-27 US disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-8444762-B2 Varnish compositions for electrical insulation and method of using the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-05-21 US disclosed
US-20120277399-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-11-01 US disclosed
US-8092722-B2 Varnish compositions for electrical insulation and method of using the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-10 US disclosed
US-8075812-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-13 US disclosed
US-20110294966-A1 VARNISH COMPOSITIONS FOR ELECTRICAL INSULATION AND METHOD OF USING THE SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2011-12-01 US disclosed
US-8025926-B2 Varnish compositions for electrical insulation and method of using the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-09-27 US disclosed
US-7781537-B2 Functionalized poly(arylene ether) composition and method SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-08-24 US disclosed
US-20100080892-A1 VARNISH COMPOSITIONS FOR ELECTRICAL INSULATION AND METHOD OF USING THE SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2010-04-01 US disclosed
US-7297370-B2 melting at least a portion of pellets or powder, the portion comprising a mixture of a functionalized polymer and a reactive monomer andflowing the molten portion into contact with the portion of the electronic or optical device GENERAL ELECTRIC COMPANY (US) 2007-11-20 US disclosed
US-7250477-B2 Thermoset composite composition, method, and article GENERAL ELECTRIC COMPANY (US) 2007-07-31 US disclosed
US-7226980-B2 Thermoset composition, method for the preparation thereof, and articles prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-06-05 US disclosed
US-7211639-B2 Composition comprising functionalized poly(arylene ether) and ethylene-alkyl (meth)acrylate copolymer, method for the preparation thereof, and articles prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-05-01 US disclosed
US-7205035-B2 Thermoset composition, method, and article GENERAL ELECTRIC COMPANY (US) 2007-04-17 US disclosed
US-20070082986-A1 Polymer composition, method, and article SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-04-12 US disclosed
US-20070080330-A1 Flame retardant composition and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-04-12 US disclosed
US-20070082987-A1 Poly(arylene ether) composition, method, and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-04-12 US disclosed
US-7199213-B2 Thermoset composition, method for the preparation thereof, and articles prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-04-03 US disclosed
US-20070066710-A1 Method for electrical insulation and insulated electrical conductor CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed