SCHEMBL25328660

SCHEMBL25328660

CCc1c(O)c(C)c(CC)c(OC)c1CC

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.34
IMPDH2 P12268 3/20 0.34
IGF1R P08069 1/20 0.32
SRC P12931 1/20 0.32
AXL P30530 1/20 0.32
PTK2 Q05397 1/20 0.32
AURKB Q96GD4 1/20 0.32
ALK Q9UM73 1/20 0.32
IMPDH1 P20839 1/20 0.31
APP P05067 1/20 0.30
AKR1B1 P15121 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25330017 0.89 IMPDH2 (0.38) ALOX5IMPDH2IGF1RSRCAXL
SCHEMBL25329338 0.87 IMPDH2 (0.44) ALOX5IMPDH2IMPDH1
SCHEMBL25329798 0.86 PTGS2 (0.34) ALOX5IMPDH2AKR1B1PTGS2
SCHEMBL25327553 0.84 IMPDH2 (0.36) ALOX5IMPDH2IMPDH1APPAKR1B1
SCHEMBL21602868 0.83 IMPDH2 (0.41) ALOX5IMPDH2IMPDH1
SCHEMBL32689518 0.83 IMPDH2 (0.41) ALOX5IMPDH2IMPDH1
SCHEMBL17431561 0.82 IMPDH2 (0.37) ALOX5IMPDH2IGF1RSRCAXL
SCHEMBL25331642 0.81 CYP1A2 (0.31)
SCHEMBL12190207 0.80 IMPDH2 (0.41) ALOX5IMPDH2IMPDH1APPAKR1B1
SCHEMBL25328865 0.79 ALOX5 (0.37) ALOX5IMPDH2IMPDH1APPAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583813-B2 Polymerization inhibitors BASF SE (DE) 2026-03-24 US disclosed
US-20230242472-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-08-03 US disclosed
EP-4161892-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-04-12 EP disclosed
CN-115697954-A Polymerization inhibitor 巴斯夫欧洲公司 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242472-A1 POLYMERIZATION INHIBITORS RCE1, CABLES1, DPYD ALOX5 1518/4885IMPDH2 1168/4885IGF1R 4005/4885
US-12583813-B2 Polymerization inhibitors PTGS1, PTGER1, POT1 ALOX5 560/4885IMPDH2 1852/4885IGF1R 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.