SCHEMBL25328865

SCHEMBL25328865

CCc1c(C)c(OC)c(C)c(CC)c1O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.37
IMPDH2 P12268 10/20 0.34
IMPDH1 P20839 1/20 0.33
PTGS2 P35354 1/20 0.33
APP P05067 1/20 0.33
AKR1B1 P15121 1/20 0.33
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12190207 0.91 IMPDH2 (0.41) ALOX5IMPDH2IMPDH1PTGS2APP
SCHEMBL25327553 0.91 IMPDH2 (0.36) ALOX5IMPDH2IMPDH1PTGS2APP
SCHEMBL19463497 0.88 IMPDH2 (0.37) ALOX5IMPDH2IMPDH1PTGS2APP
SCHEMBL25330017 0.86 IMPDH2 (0.38) ALOX5IMPDH2IMPDH1PTGS2APP
SCHEMBL26447825 0.84 IMPDH2 (0.35) ALOX5IMPDH2IMPDH1PTGS2APP
SCHEMBL17431561 0.83 IMPDH2 (0.37) ALOX5IMPDH2IMPDH1PTGS2APP
SCHEMBL25329798 0.82 PTGS2 (0.34) ALOX5IMPDH2PTGS2AKR1B1CA2
SCHEMBL21602868 0.79 IMPDH2 (0.41) ALOX5IMPDH2IMPDH1
SCHEMBL32689518 0.79 IMPDH2 (0.41) ALOX5IMPDH2IMPDH1
SCHEMBL25328660 0.79 ALOX5 (0.34) ALOX5IMPDH2IMPDH1PTGS2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583813-B2 Polymerization inhibitors BASF SE (DE) 2026-03-24 US disclosed
US-20230242472-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-08-03 US disclosed
CN-115697954-A Polymerization inhibitor 巴斯夫欧洲公司 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242472-A1 POLYMERIZATION INHIBITORS RCE1, CABLES1, DPYD ALOX5 1518/4885IMPDH2 1168/4885IMPDH1 926/4885
US-12583813-B2 Polymerization inhibitors PTGS1, PTGER1, POT1 ALOX5 560/4885IMPDH2 1852/4885IMPDH1 1245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.