SCHEMBL10050499

SCHEMBL10050499

[C-]#[N+]c1ccc(-c2c3nc(c(-c4ccc(OC)cc4)c4ccc([nH]4)c(-c4ccc(C#N)cc4)c4nc(c(-c5ccc(OC)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 1/20 0.41
▸ TERT O14746 4/20 0.40
▸ TOP1 P11387 4/20 0.39
▸ CYCS P99999 3/20 0.38
▸ CNR1 P21554 1/20 0.38
▸ ENPP2 Q13822 1/20 0.38
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ GSK3B P49841 1/20 0.36
▸ MAPKAPK2 P49137 1/20 0.35
▸ KDM1A O60341 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075062 0.91 ABCG2 (0.47) ABCG2TERTTOP1CYCSCNR1
SCHEMBL10050496 0.91 MAPT (0.36) ABCG2TERTTOP1CYCSCNR1
SCHEMBL10050497 0.84 RAB9A (0.44) MEN1KMT2A
SCHEMBL10050507 0.81 TERT (0.41) ABCG2TERTTOP1CYCSCNR1
SCHEMBL29414382 0.80 TERT (0.57) ABCG2TERTTOP1CYCSENPP2
SCHEMBL29777544 0.80 TOP1 (0.55) ABCG2TERTTOP1CYCSENPP2
SCHEMBL6513665 0.80 TOP1 (0.55) ABCG2TERTTOP1CYCSENPP2
SCHEMBL949511 0.80 TERT (0.57) ABCG2TERTTOP1CYCSENPP2
SCHEMBL10050500 0.79 MAPT (0.39) ABCG2CNR1GSK3B
SCHEMBL2338257 0.79 TERT (0.55) ABCG2TERTTOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092661-B2 Electropolymerisable monomers, soluble in an aqueous solution and comprising a metalloporphyrin BIOMERIEUX (FR) 2012-01-10 — — US disclosed
US-20090314660-A1 Novel Electropolymerisable Monomers, Soluble in an Aqueous Solution and Comprising a Metalloporphyrin BIOMERIEUX (FR) 2009-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090314660-A1 Novel Electropolymerisable Monomers, Soluble in an Aqueous Solution and Comprising a Metalloporphyrin EPS15, PPOX, ACR ABCG2 703/4885TERT 1074/4885TOP1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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