Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45963 | 0.78 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170699 | 0.76 | OPRM1 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14292473 | 0.75 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19937935 | 0.74 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12337178 | 0.74 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13847990 | 0.73 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14161036 | 0.73 | OPRK1 (0.34) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13659979 | 0.73 | OPRK1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13847992 | 0.73 | OPRK1 (0.34) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13848227 | 0.72 | OPRM1 (0.47) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420503-A1 | Process for the synthesis of 14-oxygenated morphinan-6-ones | Universität Innsbruck (AT) | 2012-02-22 | — | — | EP | disclosed |