Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050971 | 0.76 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170797 | 0.75 | OPRM1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170720 | 0.75 | OPRM1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13825005 | 0.74 | OPRM1 (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12831142 | 0.74 | OPRM1 (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13248810 | 0.74 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12091332 | 0.74 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16541860 | 0.71 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14161044 | 0.70 | OPRK1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170766 | 0.70 | OPRK1 (0.53) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |