SCHEMBL10052286

SCHEMBL10052286

CC(C)C1CC(=O)CN1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
PIK3CD O00329 1/20 0.32
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23485120 1.00 L3MBTL1 (0.33) L3MBTL1DPP4DPP8DPP9PIK3CD
SCHEMBL2707422 1.00 L3MBTL1 (0.33) L3MBTL1DPP4DPP8DPP9PIK3CD
SCHEMBL23488614 0.79 L3MBTL1 (0.43) L3MBTL1PIK3CD
SCHEMBL9980259 0.76 L3MBTL1 (0.38) L3MBTL1DPP4DPP8DPP9MAPK1
SCHEMBL2757452 0.76 MAPK1 (0.35) DPP4DPP8DPP9PIK3CDMAPK1
SCHEMBL10052288 0.74
SCHEMBL2705993 0.74
SCHEMBL14558062 0.72 MMP2 (0.36) L3MBTL1DPP4DPP8DPP9
SCHEMBL21145968 0.71 PIK3CD (0.33) DPP4DPP8DPP9PIK3CD
SCHEMBL15462354 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
US-11357828-B2 Releasable GLP-1 conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2022-06-14 US disclosed
US-20220118055-A1 RELEASABLE GLP-1 CONJUGATES FISH & RICHARDSON PC 2022-04-21 US disclosed
US-20210170045-A1 RELEASABLE ANTIBODY CONJUGATES FISH & RICHARDSON PC 2021-06-10 US disclosed
US-8623814-B2 Antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2014-01-07 US disclosed
US-8178531-B2 Antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2012-05-15 US disclosed
US-20110218175-A1 ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2011-09-08 US disclosed
US-20110206637-A1 ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218175-A1 ANTIVIRAL AGENTS EIF2AK2, HAVCR2, MAVS L3MBTL1 3897/4885DPP4 314/4885DPP8 534/4885
US-20210170045-A1 RELEASABLE ANTIBODY CONJUGATES BCR, CD47, RNASE1 L3MBTL1 956/4885DPP4 1294/4885DPP8 1065/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 L3MBTL1 3548/4885DPP4 828/4885DPP8 955/4885
US-20110206637-A1 ANTIVIRAL AGENTS EIF2AK2, ZC3HAV1, MAVS L3MBTL1 4169/4885DPP4 126/4885DPP8 273/4885
US-11357828-B2 Releasable GLP-1 conjugates GLP1R, GIPR, IAPP L3MBTL1 1957/4885DPP4 11/4885DPP8 21/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 L3MBTL1 3548/4885DPP4 828/4885DPP8 955/4885
US-20220118055-A1 RELEASABLE GLP-1 CONJUGATES GLP1R, GIPR, IAPP L3MBTL1 1957/4885DPP4 11/4885DPP8 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.