SCHEMBL10054147

SCHEMBL10054147

C1=CC2=C(CC1)Oc1ccccc1-c1cncn12

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
SETD7 Q8WTS6 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
DRD1 P21728 1/20 0.31
SLC5A7 Q9GZV3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698045 0.70 GPBAR1 (0.41) IDO1SETD7
SCHEMBL23586294 0.63 HPGD (0.31)
SCHEMBL19046240 0.63 P2RX4 (0.32)
SCHEMBL8202408 0.60 KDM4E (0.38)
SCHEMBL20902494 0.59 FAAH (0.30)
SCHEMBL1948376 0.57 IDO1 (0.50) IDO1ADORA3DRD1SLC5A7
SCHEMBL22810549 0.57 L3MBTL1 (0.40)
SCHEMBL18222130 0.56 ALOX5 (0.48)
SCHEMBL19888558 0.56 KDM4E (0.34) SETD7
SCHEMBL12215542 0.56 BCHE (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423214-A1 Light emitting materials for Electronics Solvay SA (BE) 2012-02-29 EP disclosed