Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053945 | 0.82 | HTR1A (0.45) | SIGMAR1HTR1A | |
| SCHEMBL18618012 | 0.77 | HRH2 (0.46) | SIGMAR1 | |
| SCHEMBL3648634 | 0.76 | CHRNB2 (0.47) | SIGMAR1REN | |
| SCHEMBL3650270 | 0.76 | CHRNB2 (0.47) | SIGMAR1REN | |
| Hydrochloric Acid SCHEMBL4537169 | 0.75 | SIGMAR1 (0.47) | SIGMAR1REN | |
| SCHEMBL17606834 | 0.74 | LTA4H (0.44) | SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL28496997 | 0.73 | HRH2 (0.56) | SIGMAR1 | |
| SCHEMBL28231989 | 0.73 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL30775094 | 0.73 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL28148266 | 0.73 | HSD11B1 (0.46) | SIGMAR1CYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019426-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |