SCHEMBL10056575

SCHEMBL10056575

Brc1cccc(C(c2cccc(Br)n2)(c2cccc(Br)n2)c2cccc(Br)n2)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
HTR7 P34969 2/20 0.33
HTR1A P08908 1/20 0.33
DRD2 P14416 1/20 0.33
HTR2A P28223 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA3 P34903 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007673 0.84 ALDH1A1 (0.33) TSHRGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2757632 0.80 HTR7 (0.35) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL957932 0.80 SMN1; SMN2 (0.43) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL534247 0.80 HTR7 (0.35) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL15564046 0.80 CYP3A4 (0.37) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL29427057 0.80 HTR7 (0.35) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL37428 0.80 GABRA1 (0.47) GABRA1GABRG2GABRB3GABRA3GRIN2B
SCHEMBL955898 0.80 PGK1 (0.38) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL5646151 0.77 GABRA1 (0.36) CYP3A4TSHRHTR7HTR1ADRD2
SCHEMBL1111062 0.77 IRAK4 (0.33) CYP3A4TSHRHTR7HTR1ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092925-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-7758971-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-07-20 US disclosed
US-7758971-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-07-20 US disclosed
US-7736755-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-06-15 US disclosed
US-7736755-B2 Organic electroluminescent device FUJIFILM CORPORATION (JP) 2010-06-15 US disclosed
US-20090039768-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2009-02-12 US disclosed