Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69937 | 0.79 | NPC1 (0.58) | RAB9ANPC1KMT2AMEN1TNKS | |
| SCHEMBL11860960 | 0.78 | KMT2A (0.50) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL11319698 | 0.77 | KDM4E (0.56) | RAB9ANPC1KMT2AMEN1TNKS | |
| SCHEMBL11319692 | 0.73 | NPC1 (0.71) | RAB9ANPC1KMT2AMEN1TNKS | |
| SCHEMBL11868305 | 0.73 | NPC1 (0.66) | RAB9ANPC1KMT2AMEN1TNKS | |
| SCHEMBL11866301 | 0.73 | THRB (0.54) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL8949520 | 0.73 | MAOA (0.56) | RAB9ANPC1KMT2AMEN1KDM4E | |
| SCHEMBL20317213 | 0.73 | NPC1 (0.55) | RAB9ANPC1KMT2AMEN1TNKS | |
| SCHEMBL11815286 | 0.72 | NPC1 (0.54) | RAB9ANPC1RXFP1KMT2AMEN1 | |
| SCHEMBL68516 | 0.72 | CA1 (0.53) | RAB9ANPC1KMT2AMEN1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115128-A1 | SELECTIVE PROTEIN LABELING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2012-05-10 | — | — | US | disclosed |