SCHEMBL10057791

SCHEMBL10057791

Cc1cc(Cc2cc(C)c(O)c(Cc3cc(C)c(O)c(Cc4ccc(O)cc4O)c3C)c2C)c(O)c(Cc2cc(C)c(O)c(Cc3cc(C)c(O)c(Cc4ccc(O)cc4O)c3C)c2O)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.44
ALOX5 P09917 3/20 0.38
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TYR P14679 5/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
HSPA5 P11021 1/20 0.35
CYP2D6 P10635 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278377 0.97 AMY1A (0.46) AMY1AALOX5CYP2C9CYP2C19HIF1A
SCHEMBL278748 0.97 AMY1A (0.46) AMY1AALOX5CYP2C9CYP2C19HIF1A
SCHEMBL278567 0.90 ALOX5 (0.45) ALOX5TYRMEN1MAPTKMT2A
SCHEMBL30374684 0.90 ALOX5 (0.45) ALOX5TYRMEN1MAPTKMT2A
SCHEMBL29636466 0.90 ALOX5 (0.45) ALOX5TYRMEN1MAPTKMT2A
SCHEMBL8069306 0.84 ALOX5 (0.45) AMY1AALOX5TYRMEN1MAPT
SCHEMBL7930652 0.83 AMY1A (0.51) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30703618 0.83 AMY1A (0.61) AMY1AALOX5CYP2C9CYP2C19HIF1A
SCHEMBL4059100 0.83 AMY1A (0.61) AMY1AALOX5CYP2C9CYP2C19HIF1A
SCHEMBL4004589 0.83 AMY1A (0.61) AMY1AALOX5CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-8530003-B2 Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115333-A1 POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE CD79B, BRIX1, SMARCB1 AMY1A 2796/4885ALOX5 3114/4885CYP2C9 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.