SCHEMBL10058341

SCHEMBL10058341

CS(=O)(=O)c1ccc(-c2ccc(S)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 14/20 0.52
ENPP2 Q13822 2/20 0.50
KIF11 P52732 1/20 0.46
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487226 0.93 ENPP2 (0.56) PTGS2ENPP2
Water SCHEMBL22687010 0.90 ENPP2 (0.54) PTGS2ENPP2
Water SCHEMBL28883186 0.90 ENPP2 (0.54) PTGS2ENPP2
SCHEMBL10300269 0.87 PTGS2 (0.62) PTGS2ENPP2KIF11PTGS1
SCHEMBL7677302 0.87 PTGS2 (0.62) PTGS2ENPP2KIF11PTGS1
SCHEMBL4278822 0.82 PTGS2 (0.58) PTGS2PTGS1
SCHEMBL13898960 0.80 SMN1; SMN2 (0.48) PTGS2ENPP2PTGS1
SCHEMBL2376239 0.79 ENPP2 (0.72) PTGS2ENPP2
SCHEMBL7595976 0.79 ENPP2 (0.48) PTGS2ENPP2
Ether SCHEMBL22687009 0.79 ENPP2 (0.43) PTGS2ENPP2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1519418-B1 SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING SAME SONY CORP (JP) 2012-05-02 EP disclosed