Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444872 | 0.89 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL487226 | 0.89 | ENPP2 (0.56) | PTGS2 | |
| Water SCHEMBL27918427 | 0.86 | PTGS2 (0.67) | PTGS2PTGS1 | |
| Water SCHEMBL22687010 | 0.86 | ENPP2 (0.54) | PTGS2 | |
| Water SCHEMBL28883186 | 0.86 | ENPP2 (0.54) | PTGS2 | |
| SCHEMBL6470141 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL7395459 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL10058341 | 0.82 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL7938593 | 0.82 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL9187794 | 0.82 | HSD11B1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025670-A1 | 3-(Phenyl or quinolyl)thio-1H-indole-1-acetic acid derivatives as modulators of CRTh2 receptor activity | AstraZeneca AB (SE) | 2009-02-18 | — | — | EP | disclosed |
| EP-1656346-A1 | NOVEL SUBSTITUTED 3-SULFUR INDOLES | AstraZeneca AB (SE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2004106302-A1 | NOVEL SUBSTITUTED 3-SULFUR INDOLES | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | WO | disclosed |