Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314761 | 0.81 | L3MBTL1 (0.43) | GPR6PDE4BL3MBTL1IDO1 | |
| SCHEMBL16628341 | 0.81 | HPGD (0.38) | HPGDPDE4BALDH1A1PTPN1NPC1 | |
| SCHEMBL7156421 | 0.79 | PTPN1 (0.41) | PDE4BPTPN1L3MBTL1IDO1 | |
| SCHEMBL10058953 | 0.79 | ALDH1A1 (0.41) | PDE4BALDH1A1PTPN1L3MBTL1LMNA | |
| SCHEMBL26984899 | 0.78 | PDE4B (0.34) | PDE4BPTPN1L3MBTL1P2RX3IDO1 | |
| SCHEMBL13979907 | 0.77 | LMNA (0.37) | PDE4BALDH1A1PTPN1L3MBTL1P2RX3 | |
| SCHEMBL13946932 | 0.77 | SMN1; SMN2 (0.40) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL24717170 | 0.76 | PDE4B (0.33) | PDE4BPTPN1L3MBTL1P2RX3LMNA | |
| SCHEMBL14861407 | 0.76 | USP30 (0.39) | GPR6 | |
| SCHEMBL7774635 | 0.75 | SLC6A2 (0.39) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012086735-A1 | CONDENSED HETEROCYCLIC COMPOUND | 大正製薬株式会社 (JP) | 2012-06-28 | — | — | WO | disclosed |