Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.33 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314761 | 0.80 | L3MBTL1 (0.43) | PDE4BL3MBTL1 | |
| SCHEMBL10058953 | 0.78 | ALDH1A1 (0.41) | LMNAPDE4BALDH1A1PTPN1L3MBTL1 | |
| SCHEMBL7156421 | 0.78 | PTPN1 (0.41) | PDE4BPTPN1L3MBTL1HRH3 | |
| SCHEMBL7772772 | 0.77 | RAB9A (0.44) | LMNAPDE4BSYKKDM4ENPC1 | |
| SCHEMBL818901 | 0.77 | RAB9A (0.44) | LMNAPDE4BSYKKDM4ENPC1 | |
| SCHEMBL10058951 | 0.77 | HPGD (0.36) | LMNAPDE4BNPC1ALDH1A1RAB9A | |
| SCHEMBL19991728 | 0.77 | OXTR (0.44) | PDE4BSYK | |
| SCHEMBL26984899 | 0.77 | PDE4B (0.34) | PDE4BPTPN1L3MBTL1P2RX3PDE4A | |
| SCHEMBL22320334 | 0.76 | PDE4B (0.40) | PDE4BSYKNPC1ALDH1A1MAPT | |
| SCHEMBL7794958 | 0.76 | L3MBTL1 (0.36) | LMNAKDM4EPTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174412-B1 | POLYMERIZABLE COMPOSITION SHOWING LIQUID-CRYSTAL PHASE AND OPTICALLY ANISOTROPIC FILM PREPARED FROM SAID COMPOSITION | DAINIPPON INK & CHEMICALS (JP) | 2008-12-17 | — | — | EP | disclosed |