Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655204 | 0.81 | NOS1 (0.41) | TAAR1KDM4EMAPT | |
| SCHEMBL17887717 | 0.81 | NOS1 (0.41) | TAAR1KDM4EMAPT | |
| SCHEMBL13655361 | 0.75 | MAPT (0.43) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11080147 | 0.71 | GABRP (0.39) | DGAT1TAAR1KDM1AKCNH2MAOB | |
| SCHEMBL13655358 | 0.71 | GRM5 (0.31) | — | |
| SCHEMBL13758821 | 0.69 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPT | |
| SCHEMBL13971099 | 0.68 | PRKCZ (0.39) | — | |
| SCHEMBL18708238 | 0.66 | MAPT (0.47) | DGAT1KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL2756273 | 0.66 | KDM1A (0.40) | DGAT1KDM1AKCNH2MAOBRCOR1 | |
| SCHEMBL20401774 | 0.65 | KDM1A (0.43) | DGAT1KDM1AKCNH2MAOBRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250163-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-03-28 | — | — | EP | disclosed |