Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17887717 | 0.85 | NOS1 (0.41) | MAPTKDM4EMEN1NPC1KMT2A | |
| SCHEMBL13655204 | 0.85 | NOS1 (0.41) | MAPTKDM4EMEN1NPC1KMT2A | |
| SCHEMBL13655358 | 0.82 | GRM5 (0.31) | GRM5 | |
| SCHEMBL13655085 | 0.81 | MAPT (0.47) | MAPTAPPKDM4EMEN1NPC1 | |
| SCHEMBL13655360 | 0.73 | PTGES (0.38) | FFAR1MEN1KMT2AGRM5 | |
| SCHEMBL13655362 | 0.69 | CHRNB2 (0.51) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL315312 | 0.68 | NOS1 (0.42) | MEN1NPC1KMT2ANOS1LMNA | |
| SCHEMBL3714277 | 0.64 | APP (0.55) | MAPTFFAR1APPKDM4EMEN1 | |
| SCHEMBL2114741 | 0.64 | APP (0.92) | MAPTFFAR1APPKDM4EMEN1 | |
| SCHEMBL13971099 | 0.63 | PRKCZ (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |