Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942090 | 0.93 | GABRP (0.34) | KDM4EGAAHPGDHSD17B10GABRP | |
| SCHEMBL10059440 | 0.86 | RXRA (0.35) | KDM4EGAAHPGDHSD17B10ABCC1 | |
| SCHEMBL17239587 | 0.83 | TSHR (0.35) | NOTUMRXRAALDH1A1MYC | |
| SCHEMBL17873998 | 0.83 | RXRA (0.35) | KDM4ENOTUMLIPELIPGP4HB | |
| SCHEMBL12374406 | 0.82 | MAPK1 (0.39) | LIPGLPLF11 | |
| SCHEMBL18107884 | 0.80 | LIPG (0.36) | KDM4EGPR35LIPGP4HBLPL | |
| SCHEMBL397041 | 0.79 | TSHR (0.41) | GAAHSD17B10P4HBRARARARB | |
| SCHEMBL320419 | 0.79 | TSHR (0.41) | KDM4EGAAHSD17B10P4HBRARA | |
| SCHEMBL31220241 | 0.79 | TSHR (0.41) | KDM4EGAAHSD17B10P4HBRARA | |
| SCHEMBL20519911 | 0.79 | NNMT (0.37) | LIPEF2F11PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012086735-A1 | CONDENSED HETEROCYCLIC COMPOUND | 大正製薬株式会社 (JP) | 2012-06-28 | — | — | WO | disclosed |