Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 14/20 | 1.00 |
| ▸ | CDK1 | P06493 | 4/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 1/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 1/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 1.00 |
| ▸ | GSK3B | P49841 | 16/20 | 0.90 |
| ▸ | CDK2 | P24941 | 4/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.62 |
| ▸ | CLK2 | P49760 | 2/20 | 0.62 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.62 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.62 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.62 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.62 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5403658 | 0.94 | GSK3B (0.98) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL5404007 | 0.89 | GSK3A (1.00) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL16704792 | 0.82 | GSK3A (0.70) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| Hydrochloric Acid SCHEMBL5395087 | 0.78 | GSK3A (0.68) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL14553015 | 0.74 | GSK3A (0.58) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL7255560 | 0.73 | GSK3A (0.78) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL5829062 | 0.70 | GSK3B (1.00) | GSK3ACDK1CCNB2CCNB1CCNB3 | |
| SCHEMBL4289104 | 0.70 | CDC7 (0.84) | GSK3ACDK1GSK3BCDK2CDK5 | |
| SCHEMBL5390676 | 0.70 | GSK3B (0.69) | GSK3ACDK1GSK3BCDK2CDK5 | |
| SCHEMBL1934024 | 0.69 | GSK3A (0.62) | GSK3ACDK1CCNB2CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218571-A1 | HYDROGEL DRUG DELIVERY COMPOSITION | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2022-07-14 | — | — | US | disclosed |
| US-20220133740-A1 | VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS | Frequency Therapeutics, Inc. (US) | 2022-05-05 | — | — | US | disclosed |
| US-20160024497-A1 | Compositions And Methods For Inhibiting Expression Of GSK-3 Genes | ALNYLAM PHARMACEUTICALS, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20160024497-A1 | Compositions And Methods For Inhibiting Expression Of GSK-3 Genes | ALNYLAM PHARMACEUTICALS, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20120009674-A1 | Use of a GSK-3 Inhibitor to Maintain Potency of Cultured Cells | ABT HOLDING COMPANY (US) | 2012-01-12 | — | — | US | disclosed |
| US-20110184046-A1 | Compositions And Methods For Inhibiting Expression Of GSK-3 Genes | ALNYLAM PHARMACEUTICALS, INC. | 2011-07-28 | — | — | US | disclosed |
| US-20110184046-A1 | Compositions And Methods For Inhibiting Expression Of GSK-3 Genes | ALNYLAM PHARMACEUTICALS, INC. | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218571-A1 | HYDROGEL DRUG DELIVERY COMPOSITION | PTH1R, PHPT1, PTMS | GSK3A 4522/4885CDK1 2227/4885CCNB2 2015/4885 |
| US-20110184046-A1 | Compositions And Methods For Inhibiting Expression Of GSK-3 Genes | GSK3A, GSK3B, GSKIP | GSK3A 1/4885CDK1 1035/4885CCNB2 2936/4885 |
| US-20220133740-A1 | VALPROIC ACID COMPOUNDS AND WNT AGONISTS FOR TREATING EAR DISORDERS | WNT3A, WNT1, WNT3 | GSK3A 24/4885CDK1 3063/4885CCNB2 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.