Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 18/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239166 | 0.88 | DGAT2 (0.50) | DGAT2UTS2R | |
| SCHEMBL1005953 | 0.87 | DGAT2 (0.46) | DGAT2UTS2RKCNH2 | |
| SCHEMBL1006677 | 0.85 | GPR119 (0.44) | UTS2RKCNH2 | |
| SCHEMBL1006614 | 0.79 | GPR119 (0.39) | — | |
| SCHEMBL12239164 | 0.76 | HRH1 (0.44) | UTS2RKCNH2 | |
| SCHEMBL12239158 | 0.76 | UTS2R (0.45) | UTS2R | |
| SCHEMBL1003933 | 0.76 | UTS2R (0.49) | UTS2RKCNH2 | |
| SCHEMBL12239163 | 0.75 | OPRK1 (0.43) | UTS2R | |
| SCHEMBL1006069 | 0.75 | UTS2R (0.43) | UTS2RKCNH2 | |
| SCHEMBL12239165 | 0.75 | DGAT2 (0.48) | DGAT2UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271619-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-01-12 | — | — | EP | claimed |
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | claimed |