Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI6 | Q6TGC4 | 2/20 | 0.62 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.50 |
| ▸ | KDM1A | O60341 | 7/20 | 0.49 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060566 | 0.91 | PADI6 (0.69) | PADI6PADI4KDM1ATACR2MAOA | |
| SCHEMBL10060142 | 0.91 | KDM1A (0.58) | PADI6PADI4KDM1AMAOAKDM1B | |
| SCHEMBL10060141 | 0.82 | KDM1A (0.57) | PADI6PADI4KDM1AMAOAKDM1B | |
| SCHEMBL10060235 | 0.82 | KDM1A (0.59) | PADI6PADI4KDM1AMAOAKDM1B | |
| SCHEMBL3583969 | 0.80 | PADI6 (0.64) | PADI6EPHX2NR1H4CFD | |
| SCHEMBL10061245 | 0.79 | MCHR1 (0.55) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL10060574 | 0.78 | HDAC1 (0.66) | PADI4PADI2 | |
| SCHEMBL10060139 | 0.78 | HDAC4 (0.50) | — | |
| SCHEMBL12560110 | 0.77 | PADI1 (0.56) | PADI6PADI4PADI2PDE4APDE4B | |
| SCHEMBL17531099 | 0.76 | KDM1A (0.62) | PADI6PADI4KDM1AMAOAKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108562-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108562-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | PADI4, PADI2, PADI3 | PADI6 5/4885PADI4 1/4885KDM1A 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.