SCHEMBL6130271

SCHEMBL6130271

COC(=O)N(OC)c1ccccc1CON

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 17/20 0.46
ALDH1A1 P00352 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10061323 0.84 PTGER1 (0.37) ALDH1A1
SCHEMBL1461137 0.81 ALDH1A1 (0.36) ALDH1A1
SCHEMBL21734285 0.81 LMNA (0.33) ALDH1A1ATM
SCHEMBL2371805 0.81 LMNA (0.34) ALDH1A1
SCHEMBL21734286 0.80 NISCH (0.42) ALDH1A1ATM
SCHEMBL14352104 0.80 TSHR (0.41) ALDH1A1
SCHEMBL13499618 0.80 PPARD (0.39) ALDH1A1
SCHEMBL8174719 0.79 RXRA (0.44) ALDH1A1
SCHEMBL14351893 0.78 APP (0.43) ALDH1A1
SCHEMBL13943874 0.76 PTGDR2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1347952-A4 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2005-10-26 EP disclosed
EP-1347952-A1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES Dow AgroSciences LLC (US) 2003-10-01 EP disclosed
WO-2002046142-A1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2002-06-13 WO disclosed
US-5814633-A MULTISTAGE FORMATION OF OXYIMINO ANILIDES AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-09-29 US disclosed