Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174719 | 0.88 | RXRA (0.44) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10061323 | 0.85 | PTGER1 (0.37) | MAPTTSHRGAAHTTALDH1A1 | |
| SCHEMBL6130271 | 0.80 | IDO1 (0.46) | ATMALDH1A1 | |
| SCHEMBL8657370 | 0.79 | KMT2A (0.47) | TSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8724251 | 0.79 | CASP3 (0.40) | HSD17B10HPGDKDM4EGAAALDH1A1 | |
| SCHEMBL13499618 | 0.79 | PPARD (0.39) | L3MBTL1ALDH1A1 | |
| SCHEMBL13943874 | 0.77 | PTGDR2 (0.30) | — | |
| SCHEMBL21734285 | 0.77 | LMNA (0.33) | MAPTTSHRHPGDATMKDM4E | |
| SCHEMBL2371805 | 0.77 | LMNA (0.34) | L3MBTL1MAPTTSHRHPGDKDM4E | |
| SCHEMBL1461137 | 0.77 | ALDH1A1 (0.36) | MAPTTSHRHPGDKDM4ETSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020034181-A9 | QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 中国农业大学 | 2020-08-13 | — | — | WO | disclosed |
| WO-2020034181-A1 | QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 中国农业大学 | 2020-02-20 | — | — | WO | disclosed |